A combined long-term chemical and biological know-how supported by dedicated suites and investments, positions Cerbios as a CDMO of choice for ADCs.
Cerbios is one of the front-runners and a recognized partner for the development and manufacturing of Antibody Drug Conjugates (ADCs).
The unique possibility to develop and manufacture your ADC and its components (mAb, toxin /payload, conjugate) in a single site in Lugano brings a tremendous advantage to the speed and quality of the Drug Substance.
Process development and manufacturing of tox and first clinical batches with one sole partner is the real “one-stop-shop” solution to improve effectiveness, without compromise.
We can follow you with the toxin, mAb and conjugation manufacturing from early stage development up to and including commercial supplies.
Cerbios further expands its offer of services with its PROVEO Division, with extended capacity for mAbs (at AGC Bio) and fill- finish services (at Oncotec).
Developing and manufacturing Antibody Drug Conjugates needs chemical and biological skills but not only.
The array of expertise in ADCs bioconjugationincludes:
Traditional Site-specific (Thiomab-Like)
Glycan conjugation (Synaffix)
Enzymatic (Tgase)
Traditional stochastic on Lysines and Cysteines
Flow conjugation
Expertise with multiple payloads conjugation (e.g. Maytansinoids, Auristatins, PBDs, Calicheamicin)
Unique in the CDMO landscape Cerbios can offer cGMP facility for non-cytotoxic payload conjugation to ensure full segregation from cytotoxic activities.
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