Folates are a class of water soluble compounds belonging to the Vitamin B complex which are essential for a number of metabolic functions, including processes involved in the development and metabolism of CNS and the production of DNA and RNA, primarily in infancy, adolescence and pregnancy.
Reduced folates are manufactured at Cerbios, inspected and supplied at the highest quality standards in accordance with all regulatory requirements.
Calcium Levofolinate hydrate/Levoleucovorin Calcium is a biologically active form of folate derivative used in different pharmaceutical products for various therapies.
USE
Calcium Levofolinate is used to reduce the toxic effects of some oncological therapies such as methotrexate and other medicines (Folic Acid antagonists).
It is also prescribed to treat anaemia caused by folate deficiency and in synergistic combination with the chemotherapy agent 5-fluorouracil in treating colorectal cancer (FOLFOX or FOLFIRI regimen).
CAS Number :
Formula :
Molecular Weight :
80433-71-2
C20H31CaN7O12
601.58 g/mol
FDA :
CEP :
JDMF :
CNDMF :
023437
2004-183
217MF11273
Y20180001553
Family
- Reduced folates
Therapeutic area
- Antianaemic preparations
- Detoxifying agents for antineoplastic treatment
- Vitamin preparations
Synonims
- (6S)-calcium folinate
- (6S)-N5-formyl-5,6,7,8-tetrahydrofolic acid
- Levoleucovorin
- Levoleucovorin calcium
- Calcium (6S)-folinate
- (6S)-N5-formyl-5,6,7,8-tetrahydrofolic acid
- L-glutamic acid, N-[4-[[[(6S)-2-amino-5-formyl-3,4,5, 6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1)
